Table 1 Demographics, clinical characteristics, and tumour characteristics of children diagnosed with brain tumours in Denmark from 2007 to 2017 (n = 437).
From: Early ophthalmological tumour signs and diagnostic interval in children with brain tumours
Sex, n (%) | |
Boys | 214 (49.0) |
Girls | 223 (51.0) |
Age at diagnosis, years | |
Mean (SD) | 8.1 (±4.9) |
Median (IQR) | 8.0 (8.7) |
Age group, n (%) | |
Under 5 years | 144 (33.0) |
5–11 years | 174 (39.8) |
12–18 years | 119 (27.2) |
Initial tumour sign, n (%) | |
Ophthalmological | 47 (10.8) |
General | 384 (87.9) |
No symptoms | 6 (1.4) |
Patients with ophthalmological tumour signs before diagnosis, n (%) | 226 (51.7) |
Patients examined by an ophthalmologist before diagnosis, n (%) | 164 (37.5) |
Time from initial tumour sign onset to diagnosis, weeks | |
Median (IQR) | 12.6 (30.7) |
Mean (range) | 28.8 (0.0–428.6) |
Number of tumour signs at diagnosis, mean (range) | 3.9 (0–11) |
Tumour grade, n (%) | |
Low-grade | 245 (56.1) |
High-grade | 137 (31.4) |
Unknown or not specified | 55 (12.6) |
Tumour location, n (%) | |
Infratentorial | 210 (48.1) |
Supratentorial | 200 (45.8) |
Unknown or not specified | 27 (6.2) |
Deceased at the end of follow-up, n (%) | 93 (21.3) |
Median survival of deceased children, days (range) | 380 (0–3467) |
5-year survival rate, % | 80.1 |