Table 1 Demographics, clinical characteristics, and tumour characteristics of children diagnosed with brain tumours in Denmark from 2007 to 2017 (n = 437).

From: Early ophthalmological tumour signs and diagnostic interval in children with brain tumours

Sex, n (%)

 Boys

214 (49.0)

 Girls

223 (51.0)

Age at diagnosis, years

 Mean (SD)

8.1 (±4.9)

 Median (IQR)

8.0 (8.7)

Age group, n (%)

 Under 5 years

144 (33.0)

 5–11 years

174 (39.8)

 12–18 years

119 (27.2)

Initial tumour sign, n (%)

 Ophthalmological

47 (10.8)

 General

384 (87.9)

 No symptoms

6 (1.4)

Patients with ophthalmological tumour signs before diagnosis, n (%)

226 (51.7)

Patients examined by an ophthalmologist before diagnosis, n (%)

164 (37.5)

Time from initial tumour sign onset to diagnosis, weeks

 Median (IQR)

12.6 (30.7)

 Mean (range)

28.8 (0.0–428.6)

Number of tumour signs at diagnosis, mean (range)

3.9 (0–11)

Tumour grade, n (%)

 Low-grade

245 (56.1)

 High-grade

137 (31.4)

 Unknown or not specified

55 (12.6)

Tumour location, n (%)

 Infratentorial

210 (48.1)

 Supratentorial

200 (45.8)

 Unknown or not specified

27 (6.2)

Deceased at the end of follow-up, n (%)

93 (21.3)

Median survival of deceased children, days (range)

380 (0–3467)

5-year survival rate, %

80.1

  1. SD standard deviation, IQR interquartile range.