Abstract
Background/Objectives
The trans-scleral four-point fixation technique was introduced to provide a stable lens fixation in patients with inadequate capsular support. This technique most commonly uses Akreos-AO or Micropure lenses with a Gore-Tex suture. This study aimed to report long term outcomes and complications of this technique.
Subjects/Methods
Patients who underwent insertion of a Gore-Tex sutured, scleral fixated intraocular lens between April 2019 and May 2023 in Moorfields Eye Hospital, London were identified. Operative details and postoperative outcomes were collected retrospectively from electronic case record review. Data collected included demographic details, indications for surgery, intra-operative or postoperative complications, refraction and best corrected visual acuity (BCVA).
Results
106 patients were included (median age 63 (17–83)). Indications were IOL complications (69/106, 65%); aphakia (18/106, 17%); or subluxed crystalline lens (19/106, 18%). Median follow-up was 77 weeks (range 10–200). Median postoperative BCVA was 0.3 LogMAR (IQR 0.2–0.6) at final visit with a median improvement of 0.4 LogMAR. The median postoperative spherical equivalent was −0.25 dioptres(D), with −1.75D astigmatism. Postoperative complications included cystoid macular oedema (8.5%), endophthalmitis (1.8%) and suture issues, including re-threading (1.8%), conjunctival resuturing (1%) or knot repositioning (4%). 10 patients had pre-existing corneal pathology and subsequently had a planned corneal graft.
Conclusion
Gore-Tex fixated IOLs provide good visual improvement with long-term IOL stability. This series reports all patients who underwent the surgery including those performed during the learning curve and training, showing real-world outcomes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 18 print issues and online access
$259.00 per year
only $14.39 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout


Similar content being viewed by others
Data availability
The datasets analysed during the current study are available from the corresponding author on reasonable request.
References
Kang HG, Jun JW, Choi EY, Byeon SH, Kim SS, Koh HJ, et al. Comparison of long-term surgical outcomes for scleral-fixated versus retropupillary iris-claw intraocular lens. Clin Exp Ophthalmol. 2021;49:686–95.
Shahid SM, Flores-Sánchez BC, Chan EW, Anguita R, Ahmed SN, Wickham L, et al. Scleral-fixated intraocular lens implants-evolution of surgical techniques and future developments. Eye. 2021;35:2930–61.
Vote BJ, Tranos P, Bunce C, Charteris DG, Da Cruz L. Long-term outcome of combined pars plana vitrectomy and scleral fixated sutured posterior chamber intraocular lens implantation. Am J Ophthalmol. 2006;141:308–12.
Khan MA, Omesh PG, Ryan GS, Brandon DA, Irving MR, Robert SB, et al. Scleral fixation of intraocular lenses using Gore-Tex suture: clinical outcomes and safety profile. Br J Ophthalmol. 2016;100:638.
Yalcinbayir O, Avci R, Ucan Gunduz G, Mavi Yildiz A, Cetin Efe A, Baykara M. Comparison of two techniques in posterior lens dislocations: scleral suture fixation vs. modified Yamane intrascleral lens fixation. J Fr Ophtalmol. 2022;45:13–9.
Belin PJ, Kim JH, Sheikh A, Winokur J, Rhee D, Deramo V. Incidence and risk of scleral-fixated Akreos (AO60) lens opacification: a case series. J Vitreoretin Dis. 2021;5:157–62.
Gregori NZ, Echegaray JJ, Flynn HW Jr. Opacification of Akreos hydrophilic acrylic lens after retinal detachment repair with silicone oil tamponade: a case report. Ophthalmol Ther. 2019;8:341–5.
Goel N. Clinical outcomes of combined pars plana vitrectomy and trans-scleral 4-point suture fixation of a foldable intraocular lens. Eye. 2018;32:1055–61.
Pardini D, Lucatto LF, Junior OM, Maia A, Hammamji K, Dirani A, et al. Outcomes of pars plana vitrectomy and 4-point sutured scleral fixation of AKREOS AO60 intraocular lens in clinical settings: a case series. Ophthalmol Retina. 2022;7:59–66.
McCulloch P, Altman DG, Campbell WB, Flum DR, Glasziou P, Marshall JC, et al. No surgical innovation without evaluation: the IDEAL recommendations. Lancet. 2009;374:1105–12.
Bagenal J, Lee N, Ademuyiwa AO, Nepogodiev D, Ramos-De la Medina A, Biccard B, et al. Surgical research; comic opera no more. Lancet. 2023;402:86–8.
Angelos P. Ethics and surgical innovation: challenges to the professionalism of surgeons. Int J Surg. 2013;11:S2–5.
Junqueira NB, Chaves LJ, Poli-Neto O, Scott IU, Jorge R. Scleral fixation using a hydrophilic four-haptic lens and polytetrafluoroethylene suture. Sci Rep. 2021;11:15793.
Day HR Jr, Durrani AK, Kim SJ, Patel S. Outcomes and complications of concurrent pars plana vitrectomy and scleral-fixated intraocular lens placement using gore-tex suture. J Vitreoretin Dis. 2020;4:119–24.
Patel NA, Fan KC, Yannuzzi NA, Fortun JA, Haddock LJ, Yoo SH, et al. Refractive outcomes of four-point scleral fixation of Akreos AO60 intraocular lens using gore-tex suture. Clin Ophthalmol. 2020;14:4431–7.
Bausili Portabella MM, Nadal J, Alvarez de Toledo J, Fideliz de la Paz M, Barraquer RI. Long-term outcome of scleral-sutured posterior chamber intraocular lens: a case series. Br J Ophthalmol. 2020;104:712–7.
Salvador L, Mirone S, Bianchini R, Regesta T, Patelli F, Minniti G, et al. A 20-year experience with mitral valve repair with artificial chordae in 608 patients. J Thorac Cardiovasc Surg. 2008;135:1280–7.
Lewis JS. Sulcus fixation without flaps. Ophthalmology. 1993;100:1346–50.
Chen S, Yuan G, Zhu W, Wang Q, Shi W, Zhang J. Four-point scleral fixation of an Akreos-adapt AO intraocular lens using double-strand 9-0 polypropylene suture. Retina. 2023;43:2059–63.
Ranno S, Rabbiolo GM, Lucentini S, Ruggiero E, Luccarelli SV, Lombardi L, et al. Angle-supported intraocular lens versus scleral-sutured posterior chamber intraocular lens in post-cataract surgery aphakic patients: two-year follow-up cost-effectiveness analysis. Int Ophthalmol. 2022;42:871–9.
Mishra AV, Martens R, Loh GK, Somani R, Greve MDJ, Seamone ME. Clinical outcomes of pars plana vitrectomy and polytetrafluoroethylene (Gore-Tex) scleral fixation of a monofocal aspheric intraocular lens (Akreos AO60). J Vitreoretin Dis. 2024;8:540–5.
Donachie PHJ, Sparrow JM. National Ophthalmology Database Audit: Year 4 Annual Report - the Third Prospective Report of the National Ophthalmology Database Audit. 2019. https://nodaudit.org.uk/sites/default/files/2022-06/National%20Cataract%20Audit%202019%20Comprehensive%20Report%20Year%204.pdf.
Chan EW, Yang E, Eldeeb M, Bainbridge JW, da Cruz L, Sullivan PS, et al. Contemporary outcomes and prognostic factors of 23-gauge vitrectomy for retained lens fragments after phacoemulsification. Am J Ophthalmol. 2020;219:271–83.
Güell JL, Barrera A, Manero F. A review of suturing techniques for posterior chamber lenses. Curr Opin Ophthalmol. 2004;15:44–50.
de Rojas MV, Viña S, Gestoso A, Simón P, Álvarez M. Intraocular lens explantation in Spain: indications and outcomes at a tertiary referral center from 2010 to 2018. Int Ophthalmol. 2020;40:313–23.
Leuzinger-Dias M, Lima-Fontes M, Rodrigues R, Oliveira-Ferreira C, Madeira C, Falcão-Reis F, et al. Scleral fixation of Akreos AO60 intraocular lens using gore-tex suture: an eye on visual outcomes and postoperative complications. J Ophthalmol. 2021;2021:9349323.
Negretti GS, Lai M, Petrou P, Walker R, Charteris D. Anterior chamber lens implantation in vitrectomised eyes. Eye (Lond). 2018;32:597–601.
van Severen V, Maaijwee KJM, Pennekamp CWA, Feenstra HMA, van Dijk EHC, Lindstedt EW, et al. Comparison of surgical outcomes of Carlevale sutureless scleral fixation and Artisan Aphakia intraocular lens. Acta Ophthalmol. 2024;102:491–6.
Bernal-Morales C, Navarro-Angulo MJ, Rodriguez-Maqueda M, Velazquez-Villoria D, Cubero-Parra JM, Marticorena J, et al. Predictive factors and management of macular edema after retropupillary iris-claw intraocular lens implantation in Aphakia: national multicenter audit-report 2. J Clin Med. 2023;12:436.
Author information
Authors and Affiliations
Contributions
JH contributed to study design, data collection, paper writing and redrafting. EC contributed to study design, data collection and paper redrafting. LW contributed to study design and paper redrafting.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Supplementary information
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Hind, J., Casswell, E.J. & Wickham, L. Clinical outcomes and complications during introduction of a four-point trans-scleral Gore-Tex suture fixated intraocular lens technique in a teaching hospital environment. Eye 39, 2694–2699 (2025). https://doi.org/10.1038/s41433-025-03920-0
Received:
Revised:
Accepted:
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s41433-025-03920-0


