Fig. 4: Roles of m6A modifications in microglial phagocytic activity and immune response regulation. | Genes & Immunity

Fig. 4: Roles of m6A modifications in microglial phagocytic activity and immune response regulation.

From: N6-methyladenosine RNA modification regulates microglial phagocytosis in the APP/PS1 mouse model of Alzheimer’s disease

Fig. 4

A Functional protein–protein interaction (PPI) network of m6A modification-related adaptive immune system in Alzheimer’s disease (AD) mice (i.e., APP/PS1 mice) compared to wild-type (WT) mice. Different colors represent network nodes. B We used GeneMANIA analysis to identify genes with similar functions to the 4 hub genes in (A) and construct an interactive functional association network. Interactive functional association networks show connections with the regulation of coagulation and circulation.

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