Fig. 2
From: Mutant RAMP2 causes primary open-angle glaucoma via the CRLR-cAMP axis
Mutant RAMP2 proteins formed intracellular aggregates. A lower magnification (myc staining, green) showed the expression of wild-type (WT) RAMP2 (a) and mutant RAMP2s (b–g) in COS-7 cells. (a) WT RAMP2 was diffusely distributed within the cytoplasm; (b–g) mutant RAMP2s formed intracellular aggregates. Each experiment was replicated in triplicate. Nuclei were stained with 4’-6-diamidino-2-phenylindole (DAPI). Scale bar: 10 μm.
