Table 3 Association between RDW and incident hypertension in clinically relevant subgroups

From: The association between red cell distribution width and incident hypertension in Korean adults

Subgroup

Adjusted OR (95% CI)

P value for interaction

Q1

Q2

Q3

Q4

Age (years)

    

0.703

  <40 (n = 81,063)

Reference

1.20 (1.08–1.33)

1.26 (1.13–1.41)

1.35 (1.21–1.52)

 

  ≥40 (n = 43,198)

Reference

1.17 (1.03–1.33)

1.26 (1.11–1.43)

1.26 (1.12–1.43)

 

Sex

    

0.067

  Female (n = 54,726)

Reference

1.13 (0.93–1.38)

1.28 (1.05–1.55)

1.41 (1.17–1.70)

 

  Male (n = 69,535)

Reference

1.21 (1.11–1.32)

1.28 (1.17–1.40)

1.28 (1.17–1.41)

 

BMI (kg/m2)

    

0.578

  <23.5 (n = 73,317)

Reference

1.25 (1.08–1.44)

1.37 (1.19–1.58)

1.38 (1.20–1.60)

 

  ≥23.5 (n = 50,944)

Reference

1.17 (1.06–1.29)

1.24 (1.12–1.37)

1.30 (1.18–1.44)

 

Diabetes

    

0.873

  No (n = 121,914)

Reference

1.19 (1.10–1.29)

1.28 (1.18–1.39)

1.33 (1.22–1.45)

 

  Yes (n = 2,347)

Reference

1.29 (0.89–1.87)

1.29 (0.88–1.89)

1.34 (0.89–2.00)

 

Current smoking

    

0.617

  No (n = 82,633)

Reference

1.22 (1.10–1.36)

1.26 (1.13–1.40)

1.27 (1.14–1.42)

 

  Yes (n = 26,864)

Reference

1.21 (1.05–1.39)

1.32 (1.14–1.52)

1.32 (1.14–1.53)

 

Alcohol intake (g/day)

    

0.507

  <10 (n = 73,210)

Reference

1.18 (1.04–1.34)

1.26 (1.11–1.43)

1.34 (1.18–1.52)

 

  ≥10 (n = 42,297)

Reference

1.25 (1.12–1.39)

1.32 (1.18–1.48)

1.32 (1.18–1.49)

 

Exercisea

    

0.330

  No (n = 94,962)

Reference

1.17 (1.07–1.29)

1.25 (1.14–1.38)

1.26 (1.14–1.39)

 

  Yes (n = 26,602)

Reference

1.25 (1.05–1.49)

1.38 (1.15–1.64)

1.54 (1.29–1.85)

 

hsCRP (mg/dl)

    

0.195

  <0.02 (n = 19,354)

Reference

1.55 (1.17–2.07)

1.44 (1.08–1.93)

1.52 (1.14–2.02)

 

  ≥0.02 (n = 104,907)

Reference

1.17 (1.07–1.27)

1.26 (1.16–1.38)

1.31 (1.20–1.43)

 
  1. Adjusted for age, gender, BMI, education level, hypertension, diabetes, dyslipidemia, eGFR, albumin, hsCRP, HOMA-IR, current smoking, alcohol intake, and vigorous exercise frequency.
  2. BMI body mass index, CI confidence interval, eGFR estimated glomerular filtration rate, HOMA-IR homeostatic model assessment of insulin resistance, hsCRP high-sensitivity C-reactive protein; OR odds ratio, RDW red cell distribution width, SMI skeletal muscle mass index
  3. aVigorous exercise two or more times per week
Back to article page