Table 2 Characteristics of the subject classified by ED severity
From: Deterioration of sexual function is associated with central hemodynamics in adult Japanese men
No ED (IIEF5 score; 22-25) | Mild-to-moderate ED (IIEF5 score; 12–21) | Moderate-to-severe ED (IIEF5 score; 5–11) | p-value | |
|---|---|---|---|---|
n | 68 | 138 | 47 | |
Age, years | 48 ± 17 | 61 ± 13a | 72 ± 7a,b | <0.001 |
Height, cm | 170.2 ± 6.2 | 167.1 ± 6.6a | 165.2 ± 6.0a | <0.001 |
Body mass, kg | 66.8 ± 11.7 | 64.5 ± 8.2 | 63.0 ± 9.9 | 0.090 |
Body mass index, kg/m2 | 23.0 ± 3.5 | 23.1 ± 2.5 | 23.0 ± 2.9 | 0.961 |
Total cholesterol, mg/dL | 202 ± 37 | 209 ± 36 | 212 ± 43 | 0.287 |
HDL cholesterol, mg/dL | 64 ± 17 | 64 ± 15 | 63 ± 17 | 0.986 |
LDL cholesterol, mg/dL | 116 ± 33 | 121 ± 34 | 123 ± 32 | 0.520 |
Triglycerides, mg/dL | 98 ± 50 | 107 ± 63 | 115 ± 50 | 0.313 |
Glucose, mg/dL | 99 ± 20 | 103 ± 13a | 109 ± 29a | 0.016 |
HbA1c, mg/dL | 5.4 ± 0.6 | 5.5 ± 0.5a | 57 ± 0.6a | 0.021 |
Testosterone, nmoL/L | 22.2 ± 7.4 | 20.9 ± 5.5 | 20.8 ± 10.1 | 0.426 |
Heart rate, bpm | 58 ± 8 | 60 ± 11 | 61 ± 8 | 0.169 |
Aortic AP, mmHg | 9 ± 7 | 12 ± 7a | 15 ± 6a,b | <0.001 |
Aortic APHR75, mmHg | 5 ± 5 | 8 ± 5a | 11 ± 4a,b | < 0.001 |
Aortic AI, % | 24 ± 15 | 31 ± 13a | 35 ± 8a | <0.001 |
Aortic AIHR75, % | 16 ± 15 | 24 ± 11a | 29 ± 7a,b | < 0.001 |
Time to reflection, ms | 149 ± 18 | 138 ± 17a | 131 ± 17a,b | <0.001 |
Smoking, n (%)c | 5 (7.4) | 7 (5.1) | 4 (8.5) | 0.649 |
Medication | ||||
Antihypertensive, n (%)c | 7 (10.3) | 40 (29.0) | 20 (42.6) | <0.001 |
Antihypercholesterolemic, n (%)c | 4 (5.9) | 20 (14.5) | 10 (21.3) | 0.051 |
Antihyperglycemic, n (%)c | 2 (2.9) | 5 (3.6) | 7 (14.9) | 0.008 |
Medical history | ||||
Angina, n (%)c | 1 (1.5) | 5 (3.6) | 1 (2.1) | 0.647 |
Myocardial infarction, n (%)c | 1 (1.5) | 0 (0) | 2 (4.3) | 0.065 |
Stroke, n (%)c | 0 (0) | 4 (2.9) | 2 (4.3) | 0.281 |