Table 2 Characteristics of the subject classified by ED severity

From: Deterioration of sexual function is associated with central hemodynamics in adult Japanese men

 

No ED (IIEF5 score; 22-25)

Mild-to-moderate ED (IIEF5 score; 12–21)

Moderate-to-severe ED (IIEF5 score; 5–11)

p-value

n

68

138

47

 

Age, years

48 ± 17

61 ± 13a

72 ± 7a,b

<0.001

Height, cm

170.2 ± 6.2

167.1 ± 6.6a

165.2 ± 6.0a

<0.001

Body mass, kg

66.8 ± 11.7

64.5 ± 8.2

63.0 ± 9.9

0.090

Body mass index, kg/m2

23.0 ± 3.5

23.1 ± 2.5

23.0 ± 2.9

0.961

Total cholesterol, mg/dL

202 ± 37

209 ± 36

212 ± 43

0.287

HDL cholesterol, mg/dL

64 ± 17

64 ± 15

63 ± 17

0.986

LDL cholesterol, mg/dL

116 ± 33

121 ± 34

123 ± 32

0.520

Triglycerides, mg/dL

98 ± 50

107 ± 63

115 ± 50

0.313

Glucose, mg/dL

99 ± 20

103 ± 13a

109 ± 29a

0.016

HbA1c, mg/dL

5.4 ± 0.6

5.5 ± 0.5a

57 ± 0.6a

0.021

Testosterone, nmoL/L

22.2 ± 7.4

20.9 ± 5.5

20.8 ± 10.1

0.426

Heart rate, bpm

58 ± 8

60 ± 11

61 ± 8

0.169

Aortic AP, mmHg

9 ± 7

12 ± 7a

15 ± 6a,b

<0.001

Aortic APHR75, mmHg

5 ± 5

8 ± 5a

11 ± 4a,b

<0.001

Aortic AI, %

24 ± 15

31 ± 13a

35 ± 8a

<0.001

Aortic AIHR75, %

16 ± 15

24 ± 11a

29 ± 7a,b

<0.001

Time to reflection, ms

149 ± 18

138 ± 17a

131 ± 17a,b

<0.001

Smoking, n (%)c

5 (7.4)

7 (5.1)

4 (8.5)

0.649

Medication

 Antihypertensive, n (%)c

7 (10.3)

40 (29.0)

20 (42.6)

<0.001

 Antihypercholesterolemic, n (%)c

4 (5.9)

20 (14.5)

10 (21.3)

0.051

 Antihyperglycemic, n (%)c

2 (2.9)

5 (3.6)

7 (14.9)

0.008

Medical history

 Angina, n (%)c

1 (1.5)

5 (3.6)

1 (2.1)

0.647

 Myocardial infarction, n (%)c

1 (1.5)

0 (0)

2 (4.3)

0.065

 Stroke, n (%)c

0 (0)

4 (2.9)

2 (4.3)

0.281

  1. AP augmentation pressure, APHR75 augmentation pressure corrected by 75 bpm of heart rate, AI augmentation index, AIHR75 augmentation index corrected by 75 bpm of heart rate
  2. ap < 0.05 vs. No ED
  3. bp < 0.05 vs. Mild-to-moderate ED
  4. cAnalyzed by chi-squared test