Table 6 The frequency of the ALCAM promoter methylation in control group and mild and severe PE in peripheral blood

From: Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia

Methylation status

CTL (n = 100)

Mild PE (n = 14)

Severe PE (n = 86)

Between CTL and mild PE

Between CTL and severe PE

Between mild and severe PE

UU

67

4

44

1

1

1

UM

31

7

37

0.075

3.782 (1.031–13.880)

0.054

1.817 (0.987–3.346)

0.263

2.081 (0.565–7.666)

MM

2

3

5

0.132

6.643 (0.928–47.549)

0.643

2.095 (0.380–11.556)

0.348

3.171 (0.613–16.408)

UM + MM

33

10

42

0.005

0.197 (0.057–0.676)

0.028

0.516 (0.285–0.934)

0.117

2.619 (0.762–8.998)

  1. UU un-methylated, UM hemi-methylated, MM methylated, UM + MM overall methylated, CTL control, PE preeclampsia