Table 6 The frequency of the ALCAM promoter methylation in control group and mild and severe PE in peripheral blood
From: Decreased ALCAM expression and promoter hypermethylation is associated with preeclampsia
Methylation status | CTL (n = 100) | Mild PE (n = 14) | Severe PE (n = 86) | Between CTL and mild PE | Between CTL and severe PE | Between mild and severe PE |
|---|---|---|---|---|---|---|
UU | 67 | 4 | 44 | 1 | 1 | 1 |
UM | 31 | 7 | 37 | 0.075 3.782 (1.031–13.880) | 0.054 1.817 (0.987–3.346) | 0.263 2.081 (0.565–7.666) |
MM | 2 | 3 | 5 | 0.132 6.643 (0.928–47.549) | 0.643 2.095 (0.380–11.556) | 0.348 3.171 (0.613–16.408) |
UM + MM | 33 | 10 | 42 | 0.005 0.197 (0.057–0.676) | 0.028 0.516 (0.285–0.934) | 0.117 2.619 (0.762–8.998) |