Table 7 Prediction of hypertensive retinopathy with cut-off points for vessel density and perfusion density

From: Morphological changes in and quantitative analysis of macular retinal microvasculature by optical coherence tomography angiography in hypertensive retinopathy

Variables

AUC (95% CI)

Cut-off

Sensitivity

Specifificity

Accuracy

P*

Right eye

  Superficial vessel density

0.64 (0.54, 0.73)

20.14

78.75

43.40

64.66

0.007

  Deep vessel density

0.70 (0.61, 0.79)

19.36

55.00

79.25

64.66

<0.001

  Superficial perfusion density

0.65 (0.56, 0.75)

51.25

51.25

75.47

60.90

0.001

  Deep perfusion density

0.68 (0.58, 0.77)

45.08

50.00

77.36

60.90

<0.001

  Joint index#

0.74 (0.66, 0.83)

$

65.00

77.36

69.92

<0.001

Left eye

  Superficial vessel density

0.66 (0.57, 0.75)

18.76

31.71

93.22

57.45

<0.001

  Deep vessel density

0.77 (0.69, 0.85)

20.15

81.71

66.10

75.18

<0.001

  Superficial perfusion density

0.65 (0.56, 0.74)

50.85

48.78

88.44

64.54

0.003

  Deep perfusion density

0.77 (0.69, 0.85)

47.15

75.61

67.80

72.34

<0.001

  Joint index#

0.77 (0.69, 0.85)

$

75.61

74.58

75.18

<0.001

  1. #The joint index is the combination of superficial vessel density, deep vessel density, superficial perfusion density, and deep perfusion density
  2. $There is no cut-off for joint index
  3. AUC area under the receiver operating characteristic curve, CI confifidence interval
  4. *P value compared with null hypothesis: true area = 0.5