Fig. 2 | Hypertension Research

Fig. 2

From: Renalase improves pressure overload-induced heart failure in rats by regulating extracellular signal-regulated protein kinase 1/2 signaling

Fig. 2

Renalase-human protein chip analysis results show diverse biological functions. A Recombinant renalase protein was measured by WB and CBB staining. B–E Gene ontology analysis included molecular functions, cellular components, and biological processes. B Molecular function analysis showed the differential activities of proteins related to renalase; C cellular component analysis showed the functional location of renalase protein in the cell; and D biological process analysis showed that renalase protein participates in cellular metabolism. E We predicted the biological function of renalase by KEGG. F GenePixTM Pro v6.0 analyzed the chips and showed that some proteins directly bound with renalase, such as P38, Erk1/2, and mTORC1, which play key roles in the pathological process of LVH or heart failure.

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