Table 1 Clinical characteristics of the study subjects at the study baseline
Parameter | Start | End | P value |
|---|---|---|---|
Number | 4016 | 4016 | |
Age (years) | 43 ± 9 | 49 ± 10 | <0.01 |
BMI (kg/m2) | 24.0 ± 3.1 | 24.2 ± 3.2 | <0.01 |
Current smokers (number [%]) | 1269 (31.6) | 1004 (25.0) | <0.01 |
SBP (mmHg) | 124 ± 14 | 123 ± 15 | 0.22 |
MBP (mmHg) | 91 ± 11 | 91 ± 12 | 0.87 |
DBP (mmHg) | 75 ± 11 | 76 ± 11 | 0.29 |
PP (mmHg) | 48 ± 9 | 47 ± 8 | <0.01 |
HR (bpm) | 65 ± 9 | 64 ± 10 | <0.01 |
baPWV (cm/s) | 1289 ± 187 | 1342 ± 215 | <0.01 |
radial AI | 70 ± 13 | 72 ± 13 | <0.01 |
LDL (mmol/L) | 3.25 ± 0.79 | 3.20 ± 0.77 | <0.01 |
HDL (mmol/L) | 1.61 ± 0.41 | 1.58 ± 0.40 | <0.01 |
TG (mmol/L) | 1.41 ± 0.99 | 1.37 ± 0.94 | <0.01 |
HbA1c (%) | 5.3 ± 0.6 | 5.5 ± 0.7 | <0.01 |
UA (mmol/L) | 369 ± 74 | 358 ± 72 | <0.01 |
eGFR (ml/min/1.73 m2) | 85 ± 9 | 82 ± 9 | <0.01 |
Medication | |||
For hypertension | 305 (7.6) | 614 (15.3) | <0.01 |
For dyslipidemia | 108 (2.7) | 285 (7.1) | <0.01 |
For diabetes mellitus | 96 (2.4) | 173 (4.3) | <0.01 |
For hyperuricemia | 186 (4.6) | 245 (6.1) | <0.01 |
