Fig. 2 | Hypertension Research

Fig. 2

From: U-shaped relationship between serum uric acid level and decline in renal function during a 10-year period in female subjects: BOREAS-CKD2

Fig. 2

Hazard ratio of the development of CKD by baseline uric acid levels in male subjects. a A multivariable-adjusted restricted cubic spline of the hazard ratio (HR) for the development of chronic kidney disease (CKD) by baseline uric acid levels in male subjects after adjustment for age, estimated glomerular filtration rate, BMI, systolic blood pressure, hemoglobin, albumin, urinary protein, Brinkman index, regular exercise, alcohol consumption habit, use of drugs for dyslipidemia, and diabetes mellitus at baseline and the duration of treatment with anti-hyperuricemic drugs during a 10-year follow-up period. Solid line: hazard ratio; dashed line: 95% confidence interval (CI). The reference value of uric acid was 0.6 mg/dL b HR and 95% CI for the development of CKD by quintiles of baseline uric acid levels in male subjects analyzed by a multivariable Cox proportional hazard model after adjustment of the above confounders

Back to article page