Table 1 Baseline characteristics of participants in the presence or absence of CKD and hypertension
Variables | Non-CKD + non-hypertension (n = 784) | CKD + non-hypertension (n = 108) | Non-CKD + hypertension (n = 491) | CKD + hypertension (n = 142) | P |
|---|---|---|---|---|---|
Women (%) | 68.5 | 68.5 | 63.1 | 59.9 | 0.084 |
Age (years) | 60.7 ± 9.1 | 64.2 ± 11.1 | 65.3 ± 7.8 | 67.6 ± 10.4 | <0.0001 |
BMI (kg/m2) | 22.7 ± 2.9 | 23.2 ± 3.1 | 24.0 ± 3.3 | 24.4 ± 3.4 | <0.0001 |
Current or ex-smoker (%) | 16.6 | 15.7 | 15.7 | 19.0 | 0.82 |
Current or ex-drinker (%) | 26.4 | 22.2 | 30.8 | 28.9 | 0.20 |
Hypercholesterolemia (%) | 17.2 | 25.9 | 28.1 | 23.2 | <0.0001 |
Diabetes mellitus (%) | 17.9 | 15.7 | 26.5 | 22.5 | 0.0014 |
Antihypertensive medication (%) | 0.0 | 0.0 | 61.3 | 67.6 | <0.0001 |
SBP (mmHg) | 121.1 ± 11.9 | 121.9 ± 11.5 | 141.0 ± 14.6 | 141.7 ± 16.4 | <0.0001 |
DBP (mmHg) | 68.2 ± 8.9 | 69.3 ± 9.0 | 77.0 ± 10.5 | 78.9 ± 11.5 | <0.0001 |
Proteinuria (%) | 0.0 | 43.5 | 0.0 | 45.1 | <0.0001 |
SCr (mg/dL) | 0.63 ± 0.12 | 0.82 ± 0.18 | 0.65 ± 0.12 | 0.89 ± 0.24 | <0.0001 |
eGFR (mL/min/1.73 m2) | 83.3 ± 15.8 | 62.8 ± 16.4 | 79.8 ± 14.3 | 59.2 ± 15.7 | <0.0001 |