Fig. 1 | Hypertension Research

Fig. 1

From: The ability of baroreflex activation to improve blood pressure and resistance vessel function in spontaneously hypertensive rats is dependent on stimulation parameters

Fig. 1

Experimental methodology and carotid sinus stimulation parameters in spontaneously hypertensive rats. A: Heart rate (HR) and pulsatile arterial pressure (PAP) were monitored in conscious rats for 1 h before initiating a carotid sinus stimulation protocol (1° recording). A 48-h stimulation period was performed and a  1-h recording was aquired at the 24th h (2º recording). An additional 1 h of recording was captured after stimulation was stopped (3° recording). Animals were then euthanized, and mesenteric arteries were collected for ex vivo analysis. B: A schematic diagram (1 min) depicting the short duration (5 s ON and 25 s OFF) and long duration (20 s ON and 20 s OFF) square wave pulse (3 V, 1 ms, 30 Hz) CS stimulation protocols

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