Table 1 Characteristics of patients included in the Japan Morning Surge-Home Blood Pressure (J-HOP) nocturnal blood pressure study (follow-up)

From: Sleep and cardiovascular outcomes in relation to nocturnal hypertension: the J-HOP Nocturnal Blood Pressure Study

 

Overall (n = 2236)

Sleeping hours

 

<6 h/night (n = 183)

≥6 and <9 h/night (n = 1884)

≥9 h/night (n = 169)

p value

Age, years

63.0 ± 10.3

60.1 ± 10.6

62.8 ± 10.2

69.2 ± 9.8

<0.001

Male, %

1126 (50.4)

69 (37.7)

949 (50.4)

108 (63.9)

<0.001

Body mass index, kg/m2

24.3 ± 3.5

25.3 ± 4.1

24.3 ± 3.4

23.6 ± 3.2

<0.001

Current smoker, %

264 (11.8)

23 (12.6)

218 (11.6)

23 (13.6)

0.694

Diabetes, %

560 (25.0)

47 (25.7)

465 (24.7)

48 (28.4)

0.552

Past history of cardiovascular disease, %

290 (13.0)

22 (12.0)

238 (12.6)

30 (17.8)

0.153

Antihypertensive drugs, %

1852 (82.8)

156 (85.2)

1543 (81.9)

153 (90.5)

0.011

  Calcium channel blocker

1134 (50.7)

93 (50.8)

948 (50.3)

93 (55.0)

0.502

  ACE inhibitor

146 (6.5)

9 (4.9)

121 (6.4)

16 (9.5)

0.201

  Angiotensin receptor blocker

1173 (52.5)

97 (53.0)

971 (51.5)

105 (62.1)

0.030

  Diuretic

650 (29.1)

47 (25.7)

538 (28.6)

65 (38.5)

0.014

  α-Blocker

109 (4.9)

11 (6.0)

93 (4.9)

5 (3.0)

0.394

  β-Blocker

343 (15.3)

26 (14.2)

289 (15.3)

28 (16.6)

0.828

Statin use, %

526 (23.5)

42 (23.0)

451 (23.9)

33 (19.5)

0.424

Aspirin use, %

392 (17.5)

30 (16.4)

317 (16.8)

45 (26.6)

0.005

Total cholesterol, mg/dL

204.9 ± 32.2

206.6 ± 32.6

204.7 ± 32.2

204.6 ± 32.9

0.749

HDL-cholesterol, mg/dL

58.4 ± 15.7

58.3 ± 15.0

58.5 ± 15.9

56.9 ± 14.8

0.449

Blood pressure, mmHg

  Office SBP

140.0 ± 15.3

141.0 ± 16.0

139.6 ± 15.2

142.7 ± 15.0

0.029

  Office DBP

81.9 ± 10.2

83.6 ± 10.3

81.9 ± 10.2

80.8 ± 10.4

0.031

  Morning home SBP

136.0 ± 14.7

137.9 ± 14.2

135.5 ± 14.5

139.7 ± 16.9

<0.001

  Morning home DBP

79.3 ± 9.6

81.4 ± 9.4

79.2 ± 9.5

77.8 ± 10.1

0.002

  Evening home SBP

128.7 ± 14.2

131.3 ± 13.3

128.3 ± 13.9

130.2 ± 18.0

0.009

  Evening home DBP

72.9 ± 9.3

75.8 ± 9.4

72.8 ± 9.2

70.9 ± 10.0

<0.001

  Nighttime home SBP

121.1 ± 14.7

123.7 ± 13.7

120.7 ± 14.6

122.5 ± 17.0

0.015

  Nighttime home DBP

70.0 ± 8.8

72.1 ± 9.0

69.8 ± 8.7

69.1 ± 9.3

0.001

Good sleep quality, %a

1063 (47.5)

73 (39.9)

920 (48.8)

70 (41.4)

0.017

  1. Data are expressed as mean ± standard deviation or number of patients (%)
  2. ACE angiotensin converting enzyme, DBP diastolic blood pressure, HDL high-density lipoprotein, SBP systolic blood pressure
  3. aGood sleep quality was defined as patients who answered “Never” or “Some of the time” (questions 1–4) or “Yes” (question 5) on the sleep questionnaire (see Table S1 for full details)