Table 4 Odd-ratio (OR) for the development of late and early onset preeclampsia/eclampsia (PE) according to the presence of office hypertension, and 24-hs, daytime and nocturnal hypertension in the ambulatory blood pressure monitoring (ABPM)

From: Nocturnal hypertension and risk of developing early-onset preeclampsia in high-risk pregnancies

 

Late onset PE

Early onset PE

 

Model 1

Model 2

Model 3

Model 1

Model 2

Model 3

Office hypertensiona

1.66 (0.88–3.16)

1.03 (0.51–2.10)

1.05 (0.49–2.22)

5.48 (2.87–10.48)

1.99 (0.92–4.27)

1.52 (0.67–3.44)

24-h hypertensionb

2.28 (1.35–3.86)

1.73 (0.97–3.09)

1.65 (0.89–3.05)

13.95 (6.02–32.32)

8.65 (3.54–21.14)

9.13 (3.59–23.19)

Daytime hypertensiona

2.19 (1.29–3.72)

0.88 (0.41–1.87)

1.05 (0.47–2.34)

6.52 (3.34–12.74)

1.07 (0.41–2.76)

1.27 (0.47–345)

Nocturnal hypertensionc

2.90 (1.71–4.93)

2.06 (1.26–4.55)

1.92 (0.92–4.01)

14.56 (5.60–37.85)

6.52 (2.16–18.73)

5.26 (1.67–16.60)

  1. Women without PE was the reference group. OR, odds ratio; 95% CI, 95% confidence interval. Model 1: Unadjusted, Model 2: Adjusted by systolic and diastolic blood pressure (office hypertension by systolic and diastolic ABPM, ABPM hypertension by office BP, daytime hypertension by nocturnal BP, and nocturnal hypertension by daytime BP). Model 3: Model 2 plus maternal age, gestational age at blood pressure measurements, diabetes mellitus, chronic hypertension and treatments with antihypertensives, low doses aspirin and calcium supplements. Goodness-of-fit of the fully adjusted model:
  2. aPearson 0.98 Deviance 1.00
  3. bPearson 0.96 Deviance 1.00
  4. cPearson 0.99 Deviance 1.00. No multicollinearity was observed: VIF < 5 in all Models