Table 1 Baseline clinical and histopathological characteristics and oncological outcomes of patients ≤50 years and >50 years old.
Overall | ≤50 years | >50 years | p-value* | |
|---|---|---|---|---|
Number of patients, n | 200 | 100 | 100 | |
Follow-up (months), median (IQR) | 53.5 (18–96) | 46.5 (15.25–77.5) | 62 (19.75–115) | 0.04 |
Age, (median, IQR) | 50.5 (46–65) | 46 (40–49) | 65 (59–73) | <0.001 |
Primary surgery, n (%) | 0.09 | |||
Radical circumcision | 38 (19.0) | 25 (25.0) | 13 (13.0) | |
WLE | 34 (17) | 12 (12) | 22 (22) | |
Glansectomy +/− distal corporectomy +/− SSG | 91 (45.5) | 44 (44) | 47 (47) | |
Partial penectomy +/− SSG | 20 (10) | 12 (12) | 8 (8) | |
Total penectomy | 16 (8) | 6 (6) | 10 (10) | |
Glans resurfacing | 1 (0.5) | 1 (1) | 0 (0) | |
Grade, n (%) | 0.75 | |||
1 | 1 (0.5) | 1 (1) | 0 (0) | |
1–2 | 7 (3.5) | 3 (3) | 4 (4) | |
2 | 57 (28.5) | 26 (26) | 31 (31) | |
2–3 | 75 (37.5) | 40 (40) | 35 (35) | |
3 | 60 (30) | 30 (30) | 30 (30) | |
Histology, n (%) | ||||
Sarcomatoid | 3 (1.5) | 3 (3) | 0 (0) | 0.08 |
Basaloid | 33 (16.5) | 16 (16) | 17 (17) | 0.85 |
NOS | 92 (46) | 50 (50) | 42 (42) | 0.26 |
PeIN | 84 (42) | 46 (46) | 38 (38) | 0.25 |
LS | 58 (29) | 25 (25) | 33 (33) | 0.21 |
HPV | 17 (8.5) | 12 (12) | 5 (5) | 0.08 |
pT-stage, n (%) | 0.18 | |||
1 | 104 (52) | 52 (52) | 52 (52) | |
2 | 61 (30.5) | 30 (30) | 31 (31) | |
3 | 28 (14) | 17 (17) | 11 (11) | |
4 | 7 (3.5) | 1 (1) | 6 (6) | |
pN-stage, n (%) | 0.37 | |||
x | 33 (16.5) | 12 (12) | 21 (21) | |
0 | 110 (55) | 59 (59) | 51 (51) | |
1 | 25 (12.5) | 11 (11) | 14 (14) | |
2 | 14 (7) | 7 (7) | 7 (7) | |
3 | 18 (9) | 11 (11) | 7 (7) | |
