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Long-term experience with AMS-700 CXR inflatable penile prosthesis in high-risk patients with corporal fibrosis

International Journal of Impotence Research volume 37, pages 66–71 (2025)Cite this article

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Abstract

Despite the widespread use of narrow diameter inflatable penile prosthesis (IPP) cylinders in patients with corporal fibrosis, outcomes data is sparse. We evaluated patients who underwent IPP placement with AMS™ 700 Controlled Expansion Restricted (CXR) cylinders from 2007–2021. Patient characteristics, device details, and surgical outcomes were assessed. A non-validated questionnaire was also distributed to patients to assess satisfaction. Among 982 IPPs placed over the study period at our institution, 49 (5.0%) used CXR cylinders. Indications for narrow cylinders: prior explant for infection (67.3%), ischemic priapism (16.3%), and idiopathic fibrosis (16.3%). Median corporal length was 19 cm (IQR 17–21 cm). Discordant intraoperative corporal measurements (24.5%) and RTE lengths (26.5%) were common. Post-operative complications occurred in 8 patients (16.3%) and included 3 infections (6.1%), 2 cylinder herniations (4.1%), 2 mechanical failures (4.1%), and one case of glans necrosis (2.0%). Five of these (10.2%) required explantation, while 4 (8.2%) were managed with revision. Over the follow-up period, 73.5% of patients reported satisfaction with rigidity. Primary drivers of dissatisfaction were perceived loss of penile length and girth. The AMS™ 700 CXR is a useful tool for challenging corporal fibrosis cases and shows acceptable surgical outcomes with moderate patient acceptability.

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Fig. 1: Patient satisfaction with the AMS-700 CXR™ Device.
Fig. 2: Complexities of placing penile prostheses in the setting of proximal corporal fibrosis.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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Authors and Affiliations

  1. Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Blake E. Johnson, Brian T. Langford, Maia E. VanDyke, Ethan L. Matz, Grayden S. Cook, Bryce P. Franzen & Allen F. Morey

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  1. Blake E. Johnson
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  2. Brian T. Langford
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  3. Maia E. VanDyke
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  4. Ethan L. Matz
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  5. Grayden S. Cook
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  6. Bryce P. Franzen
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  7. Allen F. Morey
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Contributions

BEJ: Survey design, survey implementation, data review, statistical analysis, manuscript preparation, manuscript review. BTL: Survey design, survey implementation, data review. MEV: Survey design, survey implementation, data review, statistical analysis, manuscript preparation, manuscript review. GSC: Survey design, survey implementation, data review. BPF: Data review, statistical analysis, manuscript preparation, manuscript review. AFM: survey design, survey implementation, manuscript review.

Corresponding author

Correspondence to Maia E. VanDyke.

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Competing interests

AFM: Boston Scientific (consultant, speaker), Coloplast Corporation (consultant, speaker). MEV: Boston Scientific (consultant). All other authors have no disclosures.

Ethics approval

This study was approved by the University of Texas Southwestern IRB (STU318 2020-1187). Given its retrospective nature, informed consent was waived after IRB review.

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Johnson, B.E., Langford, B.T., VanDyke, M.E. et al. Long-term experience with AMS-700 CXR inflatable penile prosthesis in high-risk patients with corporal fibrosis. Int J Impot Res 37, 66–71 (2025). https://doi.org/10.1038/s41443-024-00962-y

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