Table 3 Univariate and multivariate survival analysis for reoperation risk factors using cox proportional hazard models.

From: Risk factors for reoperation of inflatable penile prosthesis among an ethnically diverse urban population in a high-volume center

 

Reoperation

Infection

Characteristics

Univariate

Multivariate

Univariate

Multivariate

Pre-operative

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Age

1.01 (0.98–1.04)

0.74

1.01 (0.98–1.04)

0.63

0.99 (0.95–1.03)

0.64

0.99 (0.95–1.04)

0.70

BMI

1.03 (0.98–1.08)

0.31

1.02 (0.97–1.07)

0.49

1.03 (0.96–1.11)

0.43

1.01 (0.94–1.09)

0.79

Race (ref = Hispanic)

 Non-Hispanic White

2.12 (0.51–8.80)

0.30

1.73 (0.41–7.37)

0.46

2.15 (0.29–16.09)

0.46

1.89 (0.25–14.33)

0.54

 Non-Hispanic Black

1.24 (0.64–2.42)

0.52

1.11 (0.56–2.20)

0.76

1.82 (0.77–4.33)

0.18

1.53 (0.63–3.71)

0.35

 Other

1.04 (0.51–2.16)

0.91

1.10 (0.53–2.28)

0.80

0.53 (0.12–2.28)

0.39

0.57 (0.13–2.45)

0.45

Comorbidities

 Prostatectomy

0.68 (0.36–1.27)

0.22

0.74 (0.39–1.40)

0.35

0.50 (0.17–1.44)

0.20

0.61 (0.21–1.78)

0.36

 XRT

0.83 (0.33–2.07)

0.69

0.75 (0.30–1.90)

0.55

1.18 (0.36–3.90)

0.79

1.04 (0.31–3.48)

0.95

 Peyronie’s Disease

2.52 (1.15–5.54)

0.022

2.47 (1.10–5.58)

0.029

2.92 (1.01–8.43)

0.047

2.45 (0.82–7.35)

0.11

 Diabetes

0.76 (0.47–1.24)

0.28

0.72 (0.44–1.19)

0.21

1.10 (0.53–2.30)

0.80

1.11 (0.52–2.36)

0.78

 Hemoglobin A1c ≥ 8.0

2.22 (1.09–4.52)

0.029

2.25 (1.07–4.72)

0.032

3.13 (1.21–8.13)

0.019

3.29 (1.24–8.76)

0.017

 Hypertension

1.13 (0.63–2.06)

0.68

1.03 (0.56–1.88)

0.93

9.58 (1.30–70.47)

0.026

9.12 (1.23–67.59)

0.031

 Cardiac Disease

1.31 (0.76–2.26)

0.34

1.18 (0.67–2.05)

0.57

1.25 (0.55–2.82)

0.60

1.10 (0.48–2.51)

0.83

 Hyperlipidemia

0.96 (0.59–1.57)

0.86

0.88 (0.53–1.46)

0.62

0.97 (0.47–2.01)

0.93

0.86 (0.41–1.83)

0.70

 Chronic Kidney Disease

0.90 (0.44–1.81)

0.76

0.79 (0.39–1.62)

0.52

1.15 (0.44–3.01)

0.78

1.03 (0.39–2.75)

0.95

Smoker (ref = Never)

 Former

1.54 (0.89–2.64)

0.12

1.56 (0.90–2.69)

0.11

1.94 (0.85–4.40)

0.11

2.04 (0.89–4.67)

0.090

 Active

2.55 (1.20–5.38)

0.014

2.75 (1.30–5.85)

0.008

4.13 (1.54–11.11)

0.005

4.61 (1.71–12.42)

0.002

Intra-operative

Operative Time

1.01 (0.99–1.02)

0.13

1.01 (0.99–1.02)

0.30

1.01 (0.99–1.03)

0.13

1.01 (0.99–1.02)

0.43

Infrapubic Approach

1.46 (0.88–2.43)

0.14

1.52 (0.89–2.58)

0.13

2.38 (1.10–5.14)

0.027

2.56 (1.15–5.68)

0.021

Concurrent Surgery

 Any

1.30 (0.76–2.23)

0.35

1.39 (0.80–2.39)

0.24

1.57 (0.73–3.41)

0.25

1.79 (0.82–3.90)

0.14

 Circumcision

1.20 (0.66–2.18)

0.55

1.34 (0.73–2.46)

0.34

1.64 (0.72–3.72)

0.24

2.31 (0.98–5.43)

0.055

 Penile Modeling

1.43 (0.61–3.32)

0.41

1.35 (0.57–3.22)

0.50

1.43 (0.43–4.74)

0.56

1.11 (0.32–3.85)

0.87

Cylinder Size (ref<18cm)

 18–19

0.50 (0.24–1.05)

0.068

0.47 (0.22–0.99)

0.045

0.45 (0.15–1.39)

0.17

0.45 (0.14–1.40)

0.17

 20–21

0.62 (0.30–1.29)

0.20

0.63 (0.30–1.32)

0.22

0.64 (0.22–1.86)

0.41

0.64 (0.22–1.89)

0.42

 22+

0.71 (0.30–1.67)

0.43

0.61 (0.26–1.44)

0.26

0.62 (0.18–2.18)

0.46

0.50 (0.14–1.78)

0.28

Reservoir Size ≥ 100cc

0.85 (0.50–1.44)

0.55

0.86 (0.50–1.47)

0.58

0.78 (0.36–1.72)

0.54

0.86 (0.39–1.94)

0.72

Rear Tip Extender

0.83 (0.51–1.36)

0.46

0.75 (0.45–1.24)

0.26

0.80 (0.39–1.67)

0.56

0.70 (0.33–1.47)

0.34

Surgical Drain

1.86 (0.80–4.32)

0.15

1.91 (0.81–4.47)

0.14

1.40 (0.33–5.88)

0.65

1.25 (0.29–5.35)

0.77

EBL ≥ 25cc

2.33 (1.11–4.89)

0.026

2.45 (1.16–5.19)

0.019

2.36 (0.77–7.25)

0.13

2.26 (0.73–6.99)

0.16

Arista™ Powder Usage

0.55 (0.27–1.10)

0.090

0.38 (0.18–0.81)

0.012

0.69 (0.29–1.63)

0.40

0.39 (0.16–0.99)

0.047

  1. Due to high number of missing variables, multivariate model is only adjusted using the continuous forms of age and BMI, along with smoking status and infrapubic approach.
  2. Bold values indicate statistical significance p < 0.05.
  3. OR odds ratio, CI confidence interval, BMI body mass index, ref reference, XRT history of radiation therapy, cm centimeters, cc cubic centimeter, EBL estimated blood loss.