Abstract
Intravaginal ejaculation latency time (IELT) is traditionally considered a stable parameter in premature ejaculation (PE), although recent findings suggest that physiological, behavioural and contextual factors may influence it. This cross—sectional study assessed intraindividual variations in self-reported IELT among 119 men with PE, examining the effects of time of day, sexual position, alcohol consumption, condom use and foreplay duration. Participants completed validated questionnaires and provided IELT estimates across multiple conditions. Masturbation latency (MELT) was significantly longer than vaginal IELT (Z = 7.53, p = 3.0 × 10⁻¹⁴). Daily longest and morning IELT were significantly higher than the “average” IELT (Z = 4.06, p = 4 × 10⁻⁵; Z = 3.95, p = 8 × 10⁻⁵), whereas the shortest IELT did not differ significantly (Z = −1.26, p = 0.206). No sexual position emerged as significantly more likely to be associated with the longest or shortest IELT, although position-related IELT differences were reported (longest IELT: Z = 4.97, p = 6.7 × 10⁻⁷; shortest IELT: Z = −6.00, p = 2.0 × 10⁻⁹). IELT increased significantly after alcohol consumption (Z = 4.84, p = 1.3 × 10⁻⁶) and condom use (Z = 4.56, p = 5.1 × 10⁻⁶), while foreplay duration showed minimal impact (p = 9.3 × 10⁻⁸). These findings challenge the assumption of IELT as a fixed diagnostic parameter and highlight the influence of contextual and behavioural factors.
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The datasets generated and analysed during the current study are available from the corresponding author on reasonable request.
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Funding
EC is partially supported by the Rising Star 2024 grant of the Italian Society of Endocrinology (SIE). EAJ is partially supported by the Italian Ministry of University (MUR) PRIN Grant 2022AWB8T4, and by the #NEXTGENERATIONEU (NGEU) grant funded by the MUR, National Recovery and Resilience Plan (NRRP), project MNESYS (PE0000006) – A Multiscale integrated approach to the study of the nervous system in health and disease (DN. 1553 11.10.2022). AS was partially supported by the PRIN grant 2017S9KTNE_002. YZ is supported by the 2024 International and Hong Kong, Macao, and Taiwan Cooperation Office Construction Plan Foundation of the Third Affiliated Hospital of Sun Yat-sen University.
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YZ designed the study; HY collected the data; EC analyzed the data; EC, DZ, LZ, CW and AS participated in drafting the manuscript; EAJ and YZ supervised the research. All authors contributed to the critical revision of the manuscript and gave final approval for the version to be published.
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This study was approved by the Ethics Committee of the Third Affiliated Hospital of Sun Yat-sen University (approval no. II2023-247-02) and was performed in accordance with the ethical standards laid down in the 1964 WMA Declaration of Helsinki. All participants provided their informed consent before the study.
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Colonnello, E., Ye, J., Wang, C. et al. Self-reported variations in ejaculatory latency time in premature ejaculation: insights into contextual and behavioural factors. Int J Impot Res (2026). https://doi.org/10.1038/s41443-026-01253-4
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DOI: https://doi.org/10.1038/s41443-026-01253-4


