Fig. 5 | Nature Communications

Fig. 5

From: CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor

Fig. 5The alternative text for this image may have been generated using AI.

Heatmap showing significant RBP motif density differences in CG sequences. Heatmap is for all HCT116 and 184hTERT CGs compared to non-CG sequences. X-axis represents four CG sequence regions: penultimate (−1 exon) exon, last exon (0, terminal exon of upstream participant), first exon downstream (0, first exon of downstream participant), second exon (+1, downstream partner). Only one motif per RBP family is shown, the number of motifs in square brackets. Y-axis shows the RBP motif id and RBP name (highlighted red: CLK interactors) and protein domains associated with the listed motif. Cells with non-significant differences are colored gray. Colored cells represent a positive (red) or negative (blue) effect size. Color bars on the left y-axis represent a possible motif cluster assignment based on significance and effect size patterns

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