Fig. 5 | Nature Communications

Fig. 5

From: In situ click chemistry generation of cyclooxygenase-2 inhibitors

Fig. 5The alternative text for this image may have been generated using AI.

Thermodynamic analyses for the binding of 5-azido-pyrazole (14) to COX-2. a Raw ITC data obtained upon titration of compound 14 with COX-2 protein at room temperature (298.15 K); b Plot of the integrated heat signal as a function of the molar ratio of ligand to the protein; c Thermodynamic parameters for the binding of compound 14 with COX-2 (n = 3, ±s.e.m.)

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