Fig. 3

CIB2 deficiency disrupts stereocilia bundle morphology of the auditory hair cells. SEM images of the organs of Corti (a–c), as well as OHC (d–f) and IHC (g–i) stereocilia bundles from control heterozygous (a, d, g), Cib2 ^tm1a/tm1a (b, e, h), and Cib2 ^F91S/F91S (c, f, i) mice at the mid-cochlear location. Over-grown and retracted stereocilia are shown by arrows up and down, respectively. The IHC kinocilium does not regress properly in Cib2 mutant mice (pink). Scale bars: a–c 5 µm, (d–i) 1 µm