Fig. 5
From: Inference of neuronal functional circuitry with spike-triggered non-negative matrix factorization
Analyzing subunit overlap for ganglion cell populations. a Layout of receptive fields of fast Off ganglion cells from a single recording. Scale bar, 300 µm. Inset shows the collection of temporal filters (670 ms long) for the fast Off cells. b Layout of reconstructed subunits for the collection of cells shown in a. c Histograms of the numbers of subunits per cell for fast Off and direction-selective (DS) ganglion cells from the experiment shown in a. d Histograms of the diameters of receptive fields (black) and subunits (red). e Examples and distributions of overlapping subunits among fast Off cells (left), DS cells (center), and pairs of fast Off and DS cells (right). Scale bar, 300 µm. f Distributions of relative overlap for pairs of subunits from different ganglion cell classes (black bars), collected from five retinas (110 fast Off cells, 40 DS cells). Subunit pairs with zero overlap were excluded. For comparison, distributions of chance overlaps, obtained by shuffling the receptive field center positions within each ganglion cell class, are shown in green (shaded region corresponding to one standard deviation, obtained from repeated shuffling). All actual overlap distributions show an excess of well matching subunits (relative overlap larger than about 0.5) as compared to chance, indicating that ganglion cells within as well as across the two ganglion cell classes share input from the same bipolar cells
