Fig. 2 | Nature Communications

Fig. 2

From: Ubiquitination of stalled ribosome triggers ribosome-associated quality control

Fig. 2The alternative text for this image may have been generated using AI.

RQC requires three novel ribosome-quality control trigger factors (RQT). a Identification of RQT factors. Purified Rqt1-ribosome complex were analyzed by SDS-PAGE. Arrowed proteins were identified by mass spectrometry. b RQT factors played a crucial role in triggering step of RQC pathway. c Rqt2, Rqt3, and Rqt4 were dispensable for the ubiquitination of ribosome proteins by Rqt1. d Affinity purification of Rqt2-, Rqt3-, and Rqt4-ribosome complexes. e Rqt2, Rqt3, and Rqt4 formed a complex independent of ribosomes

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