Table 1 Discovery cohort characteristics

From: Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

Phenotypes with significant GWAS findings

 

Chickenpox

Shingles

Cold sores

Mononucleosis

Cases

107,769

16,711

25,108

17,457

Control

15,982

118,152

63,332

68,446

 

Mumps

Hepatitis B

Plantar warts

Positive TB

Cases

31,227

1425

24,994

4426

Control

54,153

218,180

37,451

84,290

 

Strep throat a

Scarlet fever

Pneumonia

Bacterial meningitis

Cases

[qt] 52,487

6812

40,600

842

Control

22,017

113,837

90,039

82,778

 

Yeast infections a

UTI frequency a

Tonsillectomy

Childhood ear infection

Cases

[qt] 52,218

[qt] 35,000

60,098

46,936

Control

10,235

33,478

113,323

74,874

 

Myringotomy

   

Cases

4138

   

Control

85,089

   

Phenotypes with no significant GWAS findings

 

Measles

Hepatitis A

Rheumatic fever

No. of colds last year a

Cases

38,219

2442

1115

[qt] 43,826

Control

47,279

217,137

88,076

15,720

 

Rubella

Chronic sinus infection

  

Cases

12,000

5291

  

Control

71,597

79,622

  
  1. GWAS genome-wide association study, qt quantitative traits, UTI urinary tract infection
  2. aStrep throat, yeast infections, UTI frequency and number of colds last year are quantitative traits
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