Table 8 MAGENTA pathway analysis on childhood ear infections GWAS

From: Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

Pathway

Pathway P value

Pathway FDR

Gene

Gene P value

SNP

SNP P value

Catalysis of the transfer of organic anions from one side of a membrane to the other

9.00E-04

0.0062

SLCO1A2

1.44E-03

rs10841784

2.76E-06

   

SLCO1B1

3.45E-03

rs2417971

5.67E-06

   

ABCC3

4.74E-03

rs186049592

1.82E-05

   

SLC22A6

3.43E-02

rs67754977

1.20E-04

   

SLC22A8

3.80E-02

rs67754977

1.20E-04

  1. FDR false discovery rate, GWAS genome-wide association study, MAGENTA Meta-Analysis Gene-set Enrichment of variaNT Associations, SNP single-nucleotide polymorphism
  2. The most significant pathway (gene sets) with a gene set enrichment FDR < 0.01 are presented
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