Fig. 4 | Nature Communications

Fig. 4

From: Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

Fig. 4

Logic-based models of the core network regulating invasive phenotypes in a bladder and b breast cancer. The black and red lines represent the type of interactions (i.e., activation and inhibition) among the interacting components. The microRNAs, receptors, and proteins are represented by rectangular nodes, whereas the EMT phenotype is represented by an ellipse in the output layer. The model is divided into three layers, i.e., the input layer (pink), the regulatory layer (yellow), and the output layer (blue)

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