Fig. 7 | Nature Communications

Fig. 7

From: Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures

Fig. 7

Kaplan–Meier plots of progression-free survival of patients with bladder and breast cancer. Plots a–c show the survival curves for patients with high and low expression of combined signatures (E2F1–FGFR1; E2F1–TGFBR1; and E2F1–FGFR1–TGFBR1) in bladder cancer patients, whereas plots d–f are for the combined signatures of E2F1–EGFR; E2F1–TGFBR2; and E2F1–EGFR–TGFBR2 in breast cancer patients. In both cases, patients with low expression of the molecular signatures have high mean survival times and vice versa. High expression of molecular signature(s) is represented as ‘_H’ (black curve) and low expression as ‘_L’ (red curve). ‘N’ is the number of patients observed with high/low expression of molecular signatures and ‘MSM’ is the mean survival month from the patient group. P-values shown in the figures are for log rank test

Back to article page