Fig. 6
Domestication of fruit sweetness and acidity in apples. a Selective sweeps from M. sieversii in Kazakhstan that co-localize with a sorbitol QTL. b Domestication sweeps from M. sylvestris that contain key genes for sugar metabolism. Distributions of XP-CLR scores are shown. Selective sweeps are marked with red bars and interesting genes are labeled above peaks. c–f Domestication of the Ma1 gene that regulates apple fruit acidity. c Distributions of nucleotide diversity (π) of M. domestica (red), M. sieversii in Kazakhstan (blue), and M. sylvestris (green) in the Ma1 genome region. d Ma1 selective sweeps during domestication from M. sieversii in Kazakhstan (blue) and M. sylvestris (green). Sweep regions are marked with filled boxes. e Distribution of F ST between M. domestica and M. sieversii in Kazakhstan in the Ma1 genome region. f Distribution of F ST between M. domestica and M. sylvestris in the Ma1 genome region. bHLH transcription factor, CTS citrate synthase, HK hexokinase, MYB transcription factor, PDK pyruvate dehydrogenase kinase, PE pectin esterase, PG polygalacturonase, PK pyruvate kinase, SBT sorbitol transporter, SS sucrose synthase, ST sugar transporter
