Table 3 Imputed SNPs surpassing genome-wide significance within and near MMP20

From: Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk

SNP

POS

A1

Discovery

Replication

Combined

   

OR

P value

OR

P value

OR

P value

rs11225333

102454685

A

2.838

4.34 × 10−7

2.206

0.012

2.673

9.71 × 10−10

rs5024119

102463359

G

2.861

4.35 × 10−7

2.370

0.007

2.736

4.07 × 10−10

rs10895322

102470256

A

2.854

4.64 × 10−7

2.361

0.007

2.728

4.54 × 10−10

rs3781788

102477556

C

2.616

1.92 × 10−7

1.813

0.048

2.404

2.42 × 10−9

rs7115479

102483150

C

2.617

1.88 × 10−7

1.809

0.049

2.403

2.44 × 10−9

rs7122793

102484945

G

2.559

3.60 × 10−7

1.657

0.103

2.322

2.79 × 10−8

rs7123742

102484946

C

2.629

1.40 × 10−7

1.650

0.106

2.372

9.75 × 10−9

rs7126560

102485553

G

2.636

1.53 × 10−7

1.810

0.049

2.417

1.93 × 10−9

rs17099063

102487065

C

2.610

2.02 × 10−7

1.797

0.052

2.395

2.82 × 10−9

rs2280211

102488131

A

2.604

2.14 × 10−7

1.795

0.052

2.390

3.09 × 10−9

rs11225344

102493269

G

2.625

2.04 × 10−7

1.931

0.024

2.443

2.95 × 10−9

rs2292731

102496405

C

2.425

2.08 × 10−7

1.637

0.075

2.211

1.93 × 10−8

rs12786739

102499728

T

2.417

2.09 × 10−7

1.631

0.077

2.204

2.15 × 10−8

rs12798540

102508004

G

2.866

4.59 × 10−8

1.385

0.358

2.492

1.31 × 10−8

rs12575154

102534875

C

2.792

1.81 × 10−7

1.470

0.296

2.473

3.14 × 10−8

rs34902925

102550821

A

2.796

1.93 × 10−7

1.484

0.285

2.480

2.92 × 10−8

  1. POS: genomic position in human genome build hg19
  2. A1: coded allele
  3. P: P value calculated by frequentist association test