Table 3 Drug-associated HLA alleles
HLA allele | Drug | Adverse reaction | Allele frequency (%) | Wright FST value | ||
|---|---|---|---|---|---|---|
Chinese | Malay | Indian | ||||
A*31:01 | Carbamazepine | Rash | 0.9 | 0 | 5.0 | 0.025 |
B*15:02 | Carbamazepine Phenytoin | SJS | 7.4 | 12.4 | 3.8 | 0.017 |
B*13:01 | Dapsone | HSS | 10.2 | 3.0 | 0.8 | 0.036 |
B*38:02 | Sulfomethoxazole | SJS/TEN | 4.6 | 4.3 | 2.9 | 0.001 |
B*57:01 | Abacavir Flucloxacilin | HSS DILI | 0 | 0.9 | 7.5 | 0.041 |
B*58:01 | Allopurinol | SJS | 10.2 | 3.0 | 0.8 | 0.036 |
