Fig. 3
From: Using ALoFT to determine the impact of putative loss-of-function variants in protein-coding genes
ALoFT classification of de novo premature stop variants from autism studies. a The top two panels show the ALoFT dominant scores of de novo premature stop mutations in autism patients and siblings; mutations in patients are further separated by gender, as shown in the bottom two panels. b ALoFT dominant prediction scores for autism de novo pLoFs in confident risk genes. In this plot, the center line represents the median value of the data, the box goes from the first quartile to the third quartile. The lower whisker goes from Q1 to the smallest non-outlier in the data set, and the upper whisker goes from Q3 to the largest non-outlier in the data set
