Fig. 3 | Nature Communications

Fig. 3

From: p190RhoGAP proteins contain pseudoGTPase domains

Fig. 3

Analysis of the degraded nucleotide binding pocket of p190RhoGAP pG1. a Alignment (top) and structural comparison (bottom) of conserved G motifs for H-Ras (PDB ID: 5P2156) and p190RhoGAP-A pG1 (p190A). Conserved threonine T35 for H-Ras is shown. Dashed box indicates region shown in b. b Close-up of the disrupted nucleotide-binding site of p190RhoGAP-A pG1 domain (left) and additional space filling model indicating the location of GTP analog when H-Ras is superposed onto the structure (right)

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