Table 1 Phenotypic characteristics of chow- and HFD-fed FasF/F and Fas∆hep mice

From: Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

 

FasF/F chow

Fas∆hep chow

FasF/F HFD

Fas∆hep HFD

Glucose (mmol/l)

9.2 ± 0.5 (n = 5)

7.7 ± 0.4 (n = 6)

10.6 ± 0.5 (n = 9)

10.3 ± 0.5## (n = 8)

Insulin (pmol/l)

165 ± 26 (n = 5)

145 ± 21 (n = 5)

332 ± 29## (n = 9)

264 ± 31 (n = 6)

FFA (mmol/l)

0.57 ± 0.06 (n = 5)

0.64 ± 0.13 (n = 6)

0.82 ± 0.06 (n = 9)

0.77 ± 0.07 (n = 8)

TG (mg/dl)

66.2 ± 5.9 (n = 5)

60.9 ± 4.3 (n = 6)

86.5 ± 6.2 (n = 9)

82.8 ± 6.8 (n = 8)

Adiponectin (µg/ml)

7.2 ± 0.7 (n = 5)

7.1 ± 0.3 (n = 6)

6.2 ± 0.4 (n = 9)

5.7 ± 0.3 (n = 8)

Leptin (pg/ml)

131 ± 44 (n = 5)

65 ± 14 (n = 6)

436 ± 87# (n = 9)

338 ± 37# (n = 8)

  1. Mice were fasted for 5 h before blood sampling. Values are expressed as mean±s.e.m.
  2. # P < 0.05 and ## p < 0.01 indicate significant differences between diets of the same genotype (ANOVA)
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