Fig. 2
From: BAD-LAMP controls TLR9 trafficking and signalling in human plasmacytoid dendritic cells

Graphical abstract of TLR9 trafficking and signalling in human pDCs. a Graphical abstract summarizing the results shown in Fig. 1 on the spatiotemporal organisation of endosomal TLR9 signalling in human pDCs. The bimodal regulation of TLR9 signalling as well as endosomal maturation is represented using rectangles in shading red for IRF7-dependent phase and early endosome and in shading blue for NF-κB-dependent phase and late endosomes