Fig. 3
From: MRAP2 regulates ghrelin receptor signaling and hunger sensing
MRAP2 is important within AGRP neurons for starvation sensing. a qPCR measurement of MRAP2 expression in the ARC of AGRPCRE/MRAP2+/+ and AGRPCRE/MRAP2fl/fl mice. b Food intake after a 24 h fast in AGRPCRE/MRAP2+/+ and AGRPCRE/MRAP2fl/fl mice (n = 8 AGRPCRE/MRAP2+/+, n = 5 AGRPCRE/MRAP2fl/fl). c–f Immunofluorescent detection of cFos expression in the arcuate nucleus of fed or fasted AGRPCRE/MRAP2+/+ and AGRPCRE/MRAP2fl/fl mice. g Quantification of fasting-induced cFos expression in the arcuate nucleus of AGRPCRE/MRAP2+/+ and AGRPCRE/MRAP2fl/fl mice (n = 3/group). Error bars are SEM. ***p<0.001, **p < 0.01, *p<0.05
