Fig. 2
From: The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus
Structure of the N-terminal domain of HPF. a The N-HPFSA (chartreuse) is interacting with the rRNA (light blue) in several locations. For example, H7 form hydrogen bonds with U965 (E. coli numbering) and Y47 is stacked with the base of G1054. b Superposition of Tth70S complex with mRNA (cyan) and three tRNAs (A-site in blue, P-site in magenta and E-site in orange, PDB code 4W2F) on one of the 70S ribosome composing the SA100S dimer presented here, demonstrating that the N-HPFSA blocks the binding sites of mRNA and the anti-codon region of all three tRNAs. The N-HPFSA location on a single 70S monomer is shown in the top right inset
