Fig. 5
From: Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi
Additional genetic alterations in DPN-like melanoma. Distant metastases of DPN harbored a combination of MAPK and b-catenin pathway activating mutations in addition to oncogenic point mutations and copy number alterations, left. Half of primary melanomas with features of DPN harbored a combination of MAPK and b-catenin pathway activating mutations, also in combination with oncogenic point mutations and copy number alterations, right
