Fig. 2 | Nature Communications

Fig. 2

From: Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology

Fig. 2

Chemo-mechanically coupled tissue response. ac Uniaxial (UA) tension relaxation experiments on (a) human amnion (hAM, n = 3, peak force 0.2 N), (b) bovine Glisson’s capsule (bGC, n = 3, peak force 0.8 N) and (c) porcine pericardium (pPC, n = 3, peak force 0.8 N) performed in 0.9% NaCl solution without (black) and with bath change to distilled water (color). The data are presented as mean (solid curve) and standard deviation (shaded area) and normalized by the corresponding tension value (T C) at the time point of change of bath. d Experimentally determined relaxed pressure (force per area) vs. volume ratio J curves for bGC sample (n = 9 stacks, black) together with the response of the biphasic model (blue). Inset: schematic illustration of the confined compression set-up. e Temporal evolution of tension in simulated UA relaxation experiment for bGC without (black) and with (blue) bath change to distilled water. f Evolution of hydrostatic (black) and osmotic (gray) pressures in the center of the specimen, corresponding to e without change of bath

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