Table 2 Dissociation constant and thermodynamic parameters of RU.521

From: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

 

rM

K d (nM)

ΔH (cal/mol)

T*ΔS (cal/mol)

ΔG (cal/mol)

RU.521

0.8071

36.17

−16290

−6134

−10150

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