Fig. 4
From: Non-canonical reader modules of BAZ1A promote recovery from DNA damage
The BD of BAZ1A promotes DNA damage recovery but is not required for SMARCA5 recruitment. a Western blot analysis of BAZ1A expression in parental, BAZ1A-KO, and BAZ1A-KO cells engineered to re-express wild-type BAZ1A, or the mutants BAZ1AΔBD (1–1424), BAZ1AEV (E1515V), and BAZ1ANY (N1509Y). b–d Confluence of the indicated cell line measured over time, before, and after a pulse of UVC light. e Accumulation of endogenous SMARCA5 at sites of DNA damage as in Fig. 2c, d. Scale bar, 20 μm. Histograms represent the mean value ± s.e.m normalized to recruitment in parental cells. P-values (P < 0.01) were calculated using a two-tailed Mann–Whitney test; n.s. not significant (P > 0.05)
