Fig. 5 | Nature Communications

Fig. 5

From: Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ

Fig. 5

PI3Kδ inhibition abrogates Treg survival. a Representative examples of Annexin staining of WT and PI3Kδ D910A/D910A nTregs transferred in the spleen of C57BL/6 mice induced with GVHD. Bar graph represents the different percentages. (*p < 0.05, t-test, n = 3/group). b Representative examples of Ki67 expression of WT and PI3Kδ D910A/D910A nTregs transferred into C57BL/6 mice induced with GVHD. Bar graph represents the different percentages. (*p < 0.05, t-test, n = 3/group). a, b The graphs show data as mean ± s.e.m. (Treg regulatory T cell; GVHD graft vs. host disease; nTreg natural regulatory T cell)

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