Fig. 4
Remaining neutralization activity after serum pre-incubation with pre-F DS-Cav1 or post-fusion F. Day 0 (a) and Day 14 (b) individual serum samples from each of the treatment groups with neutralization titers > 100 were pre-incubated with either DS-Cav1 or post-fusion F (40 µg/ml), their hRSV neutralization titers were determined and the % remaining neutralization activity was calculated relative to neutralization titers without protein pre-incubation. Asterisks indicate animals for which neutralization titers were ≤ 100. c Day 0 or Day 14 serum pools from each of the treatment groups were pre-incubated with varying concentrations of DS-Cav1 or post-fusion F (competitor) and the % remaining bRSV neutralization activity was calculated as described above. Symbols indicate the mean and error bars the SD of duplicate measurements
