Fig. 2
Distribution of early Aβ accumulation among functional networks in ADNI. The bars show the distribution of the overlap between the significant cluster of early Aβ accumulation (shown in red, see also Fig. 1a) and the functional network ROIs (shown in blue above the bars). The sum of the seven bars is therefore 100%. The pattern of early stage Aβ fibrils overlapped mostly with the DM followed by the FP network. The Jaccard coefficient describes the similarity between the early Aβ accumulation region and the functional network ROIs. It is calculated as the overlap between the early Aβ region and the network ROI/(early Aβ region + network ROI - overlap between early Aβ region and the network ROI). DA dorsal attention, DM default mode, FP frontoparietal, FT frontotemporal, SM sensory motor, VA ventral attention, VI visual network
