Table 1 MicroRNA precursors encoded in host genes with fusion transcripts in our data and in TCGA data

From: Frequent miRNA-convergent fusion gene events in breast cancer

 

Any fusion

5′ Fusion partner

3′ Fusion partner

≥ 1 Tumor

802 (61%)

691 (52%)

640 (48%)

≥ 1 Tumor and in TCGA

163 (12%)

155 (12%)

153 (12%)

≥ 1 Tumor and in TCGA breast

142 (11%)

66 (5%)

80 (6%)

Recurrent (≥ 3 tumors)

514 (39%)

426 (32%)

380 (29%)

Recurrent and in TCGA

124 (9%)

119 (9%)

92 (7%)

Recurrent and in TCGA breast

101 (8%)

51 (4%)

47 (4%)

Recurrent our data and TCGA

44 (3%)

24 (2%)

18 (1%)

Recurrent our data and TCGA breast

14 (1%)

8 (1%)

6 (0.5%)

  1. Number of miRNA precursors encoded in host genes with fusion transcripts with the corresponding percentage of all 1320 analyzed pre-miRNAs in parenthesis. 5ʹ or 3ʹ fusion partner refers to the position of the miRNA host gene and the column “any fusion” combines all precursors present in 5ʹ and/or 3ʹ fusion partner genes. Recurrent fusions were defined as occurring in at least three tumors with the host gene in the same position