Fig. 7
From: RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain
Cerebellar-dependent learning is impaired in RNF8 or UBC13 conditional knockout mice. a Schematic of delayed eye-blink conditioning assay depicting a mouse trained with a conditioned stimulus (CS: blue LED) paired with an eyeblink-eliciting unconditioned stimulus (US: periocular air puff). Depletion of RNF8 (b) or UBC13 (c) impaired performance on the eye-blink conditioning task (***p < 0.005, *p < 0.05, ANOVA followed by Fisher’s PLSD post hoc test)
