Table 1 RNF8-interacting proteins

From: RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain

Symbol

NWD-score

TSC

Herc2

11.7

107

mouse_Rnf8

9.8

6

Neurl4

6.04

25

Anks1

2.83

2

6330503K22R

2

1

Gle1

2

1

Cep170

1.71

13

Ktn1

1.16

10

Ssbp1

0.98

6

Gm16517

0.8

1

  1. Lysates from Neuro2A mouse neuroblastoma cells expressing FLAG-RNF8 were immunoprecipitated using a resin conjugated with antibodies to FLAG (FLAG M2 agarose) and analyzed by mass spectrometry. Resulting peptides were subjected to computational analyses using the ComPASS software IP-MS databases in Neuro2A cells61. High-confidence interacting proteins (HCIP) had normalized weighted D score more than 1. Total Spectra Count (TSC) of HCIPs RNF8 is also shown
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