Fig. 7 | Nature Communications

Fig. 7

From: Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer

Fig. 7

AR enhancers flanked by H2A.Zac-nucleosomes have features of active enhancers. a Heatmap of H2A.Zac (LHS), RNA polymerase II phospho S5 (RNA pol II pS5, center) and H3K27ac (RHS) ChIP-seq data at AR enhancers (n = 2232) ordered by H2A.Zac signal intensity from highest (top) to lowest at starving conditions (EtOH) and DHT treatment (DHT). Scale bars show the colorkey of the intensity of each corresponding ChIP average signal (RPM). b IGV screen shots of representative examples for AR active enhancers with H2A.Zac (LHS) or c without H2A.Zac (RHS) (highlighted in a rectangle) showing H2A.Zac (red), AR (blue) and RNA pol II pS5 (green) ChIP-seq signal at these sites (RPM)

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