Fig. 7

Model of mutually exclusive CBC complexes. Schematic diagram showing mutually exclusive CBC containing transcript complexes involved in transcription pausing (CBC-NELF-E), export of mature transcripts (CBC-ARS2-PHAX), or targeting for degradation of aberrant transcripts (CBC-ARS2-NEXT or CBC-ARS2-PAXT) defined by this work and that of others24,30,44