Fig. 6 | Nature Communications

Fig. 6

From: An extracellular matrix-related prognostic and predictive indicator for early-stage non-small cell lung cancer

Fig. 6

Predictive value of the EPPI gene signature. a Time-dependent AUC analysis of EPPI risk score and other clinical variables in GSE42127 regardless of adjuvant chemotherapy (ACT) history. b Time-dependent ROC curves at 10 year are shown with best trade-off between sensitivity and specificity (optimal cutoff = 21.7). c The EPPI risk score distribution, survival status and patient stratification based on optimal cutoff determined from ROC analysis are shown (high-risk vs. low-risk group). d Hazard ratio (HR), p-value (P), and the number of patients successfully classified (N) determined from univariate Cox regression survival analyses are shown. Black and red KM curves represent ACT and OBS (observation group: patients without ACT) group, respectively

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